Against the background of the intelligent research paradigm transformation driven by agent-based technologies, this paper sorts out the connotations of think tank research paradigms and relevant agentic organization frameworks, and points out that the application of artificial intelligence in think tank research is still largely at the stage of tool-assisted support, without forming a research paradigm compatible with organizational structures and operational mechanisms. From four aspects—governance culture, research processes, research outputs, and operational support—this paper proposes that think tanks need to enhance forward-looking prediction and technological adaptability oriented by research, promote interdisciplinary integration of research content, build human-machine collaborative research teams, integrate intelligent research methods, expand the forms of research output presentation, and improve accountability and evaluation mechanisms. The study argues that the innovation of think tank research paradigms under the agentic organization framework can promote the adjustment and transformation of think tank organizational forms and core functions, providing reference for the evolution of think tank research models in the context of "Artificial Intelligence Plus".