Improving the digital literacy and skills of vulnerable groups is an important measure to bridge the digital divide. This paper uses the method of network research to comb through Microsoft's digital literacy education practices for vulnerable groups, and focuses on analyzing Microsoft's important contributions to digital literacy education for the unemployed, the disabled and women, including improving the digital skills of the unemployed for re-employment, helping the disabled to integrate into the digital society, and improving women's career competitiveness in the digital society. Based on the characteristics of our country, this paper puts forward some suggestions for Chinese enterprises to participate in the digital literacy education in disadvantaged groups from three aspects: encouraging enterprises to participate in the digital literacy education practice, improving enterprises' ability to participate in the digital literacy education, and promoting multi-agent cooperation, so as to improve the digital literacy level of disadvantaged groups.