Current research on user health empowerment mainly focuses on the influence of users' attributes and external factors on their empowerment, but knowledge services as one of the important ways to empower users have rarely been mentioned. This paper aims to develop a health domain knowledge service model based on user health empowerment, to empower users to manage their health conditions and participate in decision-making on health issues. Based on the current research on user health empowerment and health domain knowledge services, we propose a user classification based on knowledge needs and construct a corresponding knowledge provision model by clarifying the objectives of user health empowerment-oriented knowledge services; secondly, we portray the change process of users' health knowledge reserves in the process of searching for health information and point out that the types of knowledge need to which users belong will change as the search process progresses. Finally. The matching process between users' expressed knowledge needs and knowledge resources is given, and a health domain knowledge service model for users' health empowerment is constructed.