Reading Promotion in colleges and universities helps to create and enhance the cultural atmosphere of a learning campus, which is an important part of constructing campus culture. Analyzing the current situation and existing problems of reading promotion for college students, this paper proposes that colleges and universities should focus on optimizing the knowledge structure of college students and developing their reading habits. Then, we build and improve the "great reading promotion system" with college students as the main object, and explore the concept and operation of this system from the dimensions of high positioning, great synergy, leadership, and diversification. Further, we analyze the significance and value of the construction of the "great reading promotion system" for college students in deepening the understanding of the law of talent training in colleges and universities, promoting the existing talent training system, and improving the transformation of college libraries.