With the advent of the fourth industrial revolution, China and the United States are competing in emerging technologies such as quantum computing, artificial intelligence, semiconductors, etc.. In the name of national security and intellectual property protection, the United States has imposed a severe technology blockade against China, which can be obviously seen in the Entity List, Section 337 investigation, scientific research blockade and many other cases of policy implementation in aspect of China's foreign knowledge exchange, China's high-tech development, and China's scientific and technological rise. Under the political power of the United States, China's intellectual property rights are faced with high-tech supply chain disruptions, increased corporate compliance costs, and the risk of damage to the government's international reputation, as well as risk against the development of the intellectual property industry, export transactions, and cooperative innovation. So, it is necessary to shift from the government-led one-dimensional linear governance paradigm to the multi-network governance paradigm of government macro-guidance, corporate self-discipline, and associations' collaborative efforts, to establish an overseas intellectual property dispute case database to guide enterprises to deal with Sino-US intellectual property disputes, and to guide enterprises cultivate intellectual property capabilities in innovation, litigation and layout.