Digital Humanities and Place development are both hot issues in library area nowadays. Data intensive, tools support and inter-cooperation are three characteristics of Digital Humanities Research. libraries should have rooms in promoting inter-cooperation along with supports in data and tools. On the basis of literature reviews and case studies, this article puts forward some current issues in building makerspaces and digital humanities service faced by university libraries and argued that combining both in the place theory could be a new solution. It explores the theories and methods in upgrading makerspaces to digital humanities place, based on the investigation to the iSpace project of the university of Arizona library, in order to provide reference for Chinese university libraries.