Using biblometrics to analyze the research of think-tanks on the layer of content units conforms to the trend of big data analysis in the social sciences category and can also provide new methods in think-tank research and policy research. This paper uses co-word analysis method, social networks analysis method, NLP and visualization tools to analyze the text type results of American's top think-tanks research in cyber-security during the period from 2001 to 2015. Maps of research area, research topics distribution network and content evolution were drawn. American think-tanks' research in cybersecurity has a global coverage area. There are four research agendas: defense security and counter-terrorism, international strategy, cyberspace development governance and infrastructure, public information policy and law.