对公共卫生领域多本体进行融合，快速构建综合本体，形成重大突发公共卫生事件知识库，有助于为应急决策提供专业化的知识服务。文章在复用疫苗本体、人类疾病本体、症状本体的基础上，首先进行本体的形式合并，然后利用Word2vec方法和Owlready2功能模块完成本体语义融合，实现公共卫生领域多本体融合。实验表明，所构建的综合本体语义关系准确度较高，能够从多维度视角对公共卫生领域知识进行表示，为有效应对突发重大公共卫生事件风险提供决策参考。

Multiple ontology in the field of public health have been integrated to a comprehensive knowledge base for major public health emergencies, especially in decision-making. Based on the reuse of Vaccine Ontology, Human Disease Ontology, and Symptom Ontology, on one hand, the formal merging of ontology is completed with the help of Protégé ontology editing tool, and on the other hand, the semantic fusion of ontology is completed by using Word2vec and Owlready2 to achieve the overall fusion of multiple ontology in the public health domain. The experiments indicated that the comprehensive ontology constructed by this method has high accuracy of semantic relationships and represent knowledge in the public health domain from a multidimensional perspective, providing decision support in the process of effective response to the risk of major public health emergencies.