：从国际合作研究项目产出层面分析我国参与国际科研合作的情况，对科技政策制定者、科研管理人员制定与优化国际科研合作政策、管理规章制定等具有重要意义。文章以NSFC 2001-2018年资助的"重大国际（地区）合作研究项目"的产出论文为研究对象，通过文献计量学、社会网络分析、波士顿矩阵分析的方法分析了NSFC国际合作研究项目的国际科研合作特征。结果表明："重大国际（地区）合作研究项目"产出论文一直处于稳步上升的趋势；从整体合作网络来看，参与合作的国家有99个，合作网络具有高度的连通性和集团化特征，但网络密度不高，新的合作关系有待进一步建立；从时间演化和学科领域上来看，各阶段和各学科领域的国际科研合作网络略有差异；不同国家在NSFC国际合作研究项目的合作中处于不同的水平，发展型和兴盛型国家相对较多；与我国合作倾向性较显著的国家有美国、英国、澳大利亚、加拿大、德国、日本、瑞典等，美国尤为突出，且各学科领域各具特色；我国在NSFC国际合作研究项目的合作研究中起重要的引领和主导作用，其主导的国际合作论文以双边合作为主，而多边合作相对较少。建议我国进一步提高国际科研合作深度与广度、注重与各国在特色领域开展合作、优化双多边国际科研合作机制。

Analysis on China's international research collaboration from the point of output of international collaboration research projects is of great significance to the formulation and optimization of international research collaboration policies and management regulations for science and technology policy makers and research managers. This paper studied the output papers of the project supported by major international (regional) joint research program funded by NSFC in 2001-2018 and analyzed the characteristics of China's international research collaboration with methods of bibliometric, social network analysis and BCG Matrix analysis. The output papers of the project supported by major international (regional) joint research program funded by NSFC have been steadily rising. From the perspective of the overall collaboration network, it showed that there are 99 countries participating in the collaboration and the collaboration network has a high degree of connectivity and grouping. However, the network density is not high, and the new partnership needs to be further established. From the perspective of time evolution and subject areas, it is slightly different for the international research collaboration network at each stage and across various subject areas. The level of collaboration is uneven between different countries and the number of developing and prosperous countries is relatively more. The countries with more prominent collaboration with China include the United States, Britain, Australia, Canada, Germany, Japan, Sweden, etc., especially United States, and each subject has its own characteristics. China has played an important leading role in international research collaboration of China’s international collaboration research project funded by NSFC. The international collaboration leaded by China are mainly bilateral collaboration, while multilateral is relatively rare. It is suggested that China should further enhance the depth and breadth of international research collaboration, focus on collaboration with various countries in the field of specialization, and optimize the bilateral and multilateral international research collaboration mechanism.