：新冠肺炎疫情已成为国家重大公共卫生安全突发事件。结合这次重大疫情应对过程，思考情报学和情报工作的作用具有重大的现实意义。文章从情报学视角剖析此次疫情发生、发展与抗击过程中所出现的信息与情报问题；立足总体国家安全观和新“大情报观”，提出国家公共卫生突发事件应对的情报体系框架，并分别对国家公共卫生突发事件预防与应急响应中的情报机制，情报嵌入的预测预警和应急管理系统，基于“数据－信息－知识－情报”信息链的情报工作体系和民众的信息素养与健康促进支持体系进行了阐述，以促进情报学与公共卫生安全领域的交叉与融合，促进公共卫生重大突发事件应对机制和应急管理体系完善。

The outbreak of COVID-19 has become a major public health emergency in China. It is of great practical significance to reflect on the role of information science and information work in the response to this major infection. From the perspective of information science, this paper analyzes the information and intelligence problems in the epidemic outbreak and development. Based on the Overall National Security Concept and a new “big intelligence view”, the paper also proposes the response information system framework of the national public health emergency,intelligence-embedded early warning and emergency management systems, intelligence mechanism focusing on the prevention and emergency response of the country's public health emergencies, intelligence system based on the "data - information - knowledge - intelligence" information chain, information literacy and health promotion support system, in order to facilitate crossover and integration of information science and public health security system, and improve response mechanism of the major public health emergency.