：文章采用历史分析方法，通过对各时期科学组织范式所涉及到的研究对象、组织结构及科研机构的演进分析，梳理了科学组织范式的转变情况，同时对科研机构在科学组织体系中的作用及其历史沿革进行了剖析。结合未来数据驱动科学、协作科学、开放科学和公民科学的发展趋势，提出当前科研机构正处于数据密集型的科学范式发展进程中，跨机构、跨学科、平台化、体系化、分工细化、开放协作的特征愈加突出，全新的科学组织范式正在形成。

The paper adopts a historical analysis method. By analyzing the transformation of the main research objects, organizational structure and the kinds of scientific research institutions of scientific organization paradigm in each period, we finally sort out the transformation of the scientific organization paradigm, and deeply analyze the historical evolution of scientific research institutions. Based on the development tendency of data-driven science, collaborative science, open science and citizen science, the author believes that scientific research institutions are developing to data-intensive scientific paradigm, and the management paradigm shows more characteristics of cross-institution, inter-discipline, openness and clear responsibility. In the future, the public need to take part in scientific research activities with the guidance of an open-participation scientific research organization paradigm, thus promoting the scientific research industry to move forward.